RESUMO
Coronavirus disease, since its first case reported in China in 2019, has increased at an exponential rate globally, still growing strong and challenging the Healthcare System Globally. It primarily causes Pneumonia by infiltrating the respiratory tract. However, recent studies detecting SARS-COV RNA in saliva; and affinity of the virus to ACE2 receptors which are abundantly found in epithelial lining of oral mucosa suggest that the oral cavity might probably be the first contact area for the Coronavirus. The aim of this review is to compile and present evidence-based overview of oral manifestations of COVID-19, with a view to presenting a means of early disease detection. The literature shows that the most frequently affected sites in the oral cavity are tongue, lips and palate with varied manifestations like nonspecific oral Ulcerations/blisters, Dysgeusia, Xerostomia due to reduced salivary flow, oral candidiasis and Gingivitis. The occurrence of oral lesions in COVID patients could be multifactorial; due to direct or indirect action of SARS-COV2 on oral mucosa, secondary to the therapeutic drugs used in COVID-19 treatment; lowered general health status following prolonged hospitalisation and co-infections. COVID-19 associated oral manifestations may be underreported due to lack of knowledge among Physicians and Dentists. They should be sensitized to perform a thorough oral examination in COVID affected patients to provide an early diagnosis of the disease and take up measures to limit the progression and spread of disease